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Hyperthyroidism

Hyperthyroidism is a condition that occurs when there is too much thyroid hormone in the body. The hormones thyroxine and tri-iodothyronine are produced by the thyroid gland and play a major role in determining the body's metabolic rate. When there is excess amount of thyroid hormones, it will lead to a faster metabolism resulting in hyperthyroidism. Hyperthyroidism occurs when thyroid cells trap excess iodine and produce excessive thyroid hormone. Sometimes the cause is damaged or inflamed thyroid cells. A person suffering from hyperthyroidism experiences excessive sweating and rapid heart rate (palpitations) and tremors. Such persons may notice loss of weight and extreme fatigue. These symptoms appear gradually and may sometimes go unnoticed. A person suffering from hyperthyroidism may feel nervous and notice muscle weakness. Women who are suffering from hyperthyroidism tend to have light menstrual periods or may even miss few cycles. Hair becomes brittle and skin becomes warm and moist. A person may appear agitated and confused. Patients suffering from hyperthyroidism often notice swelling at the base of the neck.


Thyroid Scan is used to measure the activity of the thyroid gland with radioactive substance. The blood TSH levels are measured to check for increased production of thyroid hormone. Graves Disease is an autoimmune disease that results in an overactive thyroid gland. This in turn leads to hyperthyroidism. Thyroiditis or inflammation of the thyroid gland is yet another cause for hyperthyroidism. Goiter or toxic nodule on the thyroid gland can be another cause for hyperthyroidism.


Anti thyroid drugs are used to control the production of thyroid hormone. These drugs include methimazole (Tapazole) and propylthiouracil (PTU). Radioactive Iodine treatment for hyperthyroidism involves a pill or liquid that is administered to the patient so as to ablate a hyperactive gland. Radioactive iodine therapy destroys only local cells and is generally given as a one-dose treatment. It is essential to monitor this treatment since it may lead to destroy too many thyroid cells and even lead to hypothyroidism. This treatment for hyperthyroidism is not used on pregnant or lactating women. Surgery is used to remove thyroid gland but this procedure is not without possible complications. Removal of too much tissue leads to hypothyroidism and often nerves connected with the vocal chords might be affected.


Thermogenesis

Thermogenesis - heat production in the body is controlled by hormones like Thyroid hormone, Norepinephrine and Leptin. Some food substances (thermogenics) can also stimulate the process of thermogenesis. For example Chilies, Capsicum, Ginger and substances like Ephedra and Caffeine are known to stimulate thermogenesis - and for this reason, they might be used to increase the energy expenditure well above the basal metabolic rate of the body in obese individuals.


Weight Loss by any means is often hard to maintain in most people. The increasing obesity levels in many countries point to many underlying causes:

High Calorie Food
Sedentary Lifestyle
Increased prevalence of mechanical aid in daily routines.


Adaptive Thermogenesis : The collective Behavioral, Metabolic, Neuroendocrine actions may play a role in this Adaptive Thermogenesis - the ability of the body to 'adapt' to negative energy balance. Adaptive thermogenesis reduces the chances of successful body weight loss. This might be in addition to the Homeostasis - the ability of a human body to maintain a stable state of equilibrium under varying impetus. Some people are known to display a very narrow range of weight loss/ weight gain even under exceptional circumstances.



Thyroid

Thyroid is a gland in the neck overlying the windpipe that regulates the speed of metabolic processes by producing a hormone with the eponymous name thyroxin. Thyroid is an endocrine gland. The thyroid gland which resembles a butterfly, sits astride the trachea. Its secretion - thyroxin, a hormone that regulates the metabolic activity of the body. Too much thyroxin races the metabolism resulting in weight loss, temperature elevation, nervousness and irritability. On the other hand, too little thyroxin slows down the metabolism rate resulting in deep voice, weight gain and water retention. This can result in retardation in physical growth and mental development in children. Both conditions equally affect hair and skin growth, bowel function and menstrual flow.

The thyroid gland is often enlarged whether it is secreting too much hormone, too little or even when it is functioning normally. The thyroid is controlled by the pituitary gland, which secretes Thyroid Stimulating Hormone (TSH) in response to the amount of thyroxin in the blood. TSH increases the amount of thyroxin secreted by the thyroid and also causes the thyroid gland to grow.




Hyperthyroid Goiter : If the amount of TSH is high, the thyroid will both enlarge and secrete too much thyroxin. The result is termed as Hyperthyroidism with a goiter. Graves' disease is the most common form of this disorder.



Euthyroid goiter : If dietary iodine is insufficient, too little thyroxin will be secreted and the pituitary will sense the deficiency and produce more TSH. The thyroid gland will enlarge enough to make sufficient thyroxin.

Hypothyroid goiter: If dietary iodine is severely low, even an enlarged gland will not be able to make enough thyroxin. The gland may keep growing under the influence of TSH, but it may never make enough thyroxin.

An endocrinologist who specializes in the endocrine system can also be consulted for thyroid problems and diseases. Specialists who deal with thyroid problem are called thyroidologists. Thryoidologist and endocrinologist are specially trained doctors who diagnose and treat diseases affecting the thyroid gland. A thyroid specialist continues specialized education focused on thyroid issues after obtaining a Masters degree in medicine. He is qualified and trained to treat conditions that are complex and involve many systems within the body that may be affected due to thyroid imbalance.


A primary care doctor too often misses the diagnosis of a thyroid disease. Sometimes primary care doctors refer patients to a thyroid specialist when there is problem in the endocrine/ hormone systems. Thyroid specialists treat patients with too much or too little thyroid hormone. The thyroid specialist helps the patients to reach a hormone balance by replacing or blocking thyroid hormone. Thyroid specialists also receive special training to manage patients with thyroid growths or thyroid cancer and enlarged thyroid glands. There are times when the services of a thryoidologist or an endocrinologist become absolutely necessary.


  • A thyroid specialist has to be consulted when a patient is suffering from the hyperthyroid autoimmune - Graves' disease. This is a condition which can be treated only by a thyroid specialist and not by a regular GP. Graves's disease and hyperthyroid management involves a number of therapies, anti thyroid drug use, radioactive iodine treatments and even surgery if necessary.
  • Evaluation and treatment for thyroid nodule can be rendered only by thyroid specialists. Thyroid nodule is evaluated by ultrasound and fine needle biopsy process. This is done to rule out the possibility of thyroid cancer.
  • Thyroid cancer is rare and less than 15000 new cases are diagnosed every year. An expert thyroid specialist is highly recommended to diagnose, evaluate, treat and help in long term follow up and support management of thyroid cancer.
  • Thyroid surgery is performed when the gland becomes so large that is cosmetically disfiguring. This is normally done if a thyroid has markedly enlarged for years. Thyroid surgery should be performed by an experienced thyroid surgeon. Only an experienced thyroid surgeon can handle the complications that can arise due to thyroid surgery.
  • A thyroid specialist can assess hypothyroidism levels. This is done by evaluation of TSH level. S/He considers other options such as symptoms, family history and clinical factors to make a thyroid diagnosis.
  • After a person has been diagnosed for hypothyroidism, a thyroid specialist treats and manages the patient for other signs and symptoms as well. Such symptoms are weight gain, depression, brain fog, hair loss, shortness of breath, intolerance to heat and cold, muscle aches and joint pains, constipation, carpal tunnel, high cholesterol, infertility, Fibromyalgia and chronic fatigue syndrome.

Tags: #Hyperthyroidism #Thermogenesis #Thyroid
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Collection of Pages - Last revised Date: November 24, 2024